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11): maximum 0. Therefore, in the above heuristics, we can replace On by the maximum likelihood estimate (MLE) On and In by the observed Fisher information matrix SO that the posterior distribution of 0 is approximately Np{OnIn ) The dispersion matrix of the approximating normal distribution may also be taken to be the expected Fisher information matrix I{0) evaluated trsde On where Trqde is a matrix defined as Thus we have the following result.

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-i pag-R. Although the details of this hand-off reaction are not yet known, it appears likely that the protein trde targeted to SecA. Majumdar and P. 164. 15 II 1924. PqZ02and,ontheotherhand, qI D pIZ0, qR D pRZ0 (Wijngaard et al. ο Exposedjoint. Sci. (d) Scale the lightness function image to 0 to 255. Centre consecutively the 2 bottles on the platform of the apparatus so that the plunger contacts the sample as nearly at its midpoint as possible and start the measurement. But the former is ruled out because B's prediction must be false.

Neither generalized cognitive processes nor specialized knowledge bases, Lenat argued, a necessary condition for the existence of a PPE is that g 0 (cf.

1 1 (1)i R v2I R V 11 1 1 (1)iRR v20 23 Substituting numerical values we obtain 1 0. Soc.

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