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E Figure 3. Multi-protein cytoskeletal complexes within focal contacts-me- chanical linkages between ligand- bound integrins and cytoskeletal struc- tures. It should be noted that subsequent thermal annealing to remove the PAMAM cores results in a nanoporous network that has a dielectric constant (k) of ca. 2 to 7. The chest radiograph typically demonstrates diffuse infiltrates, which are most prominent in the lower lobes, where a reticulonodular pattern is characteristic and may be visualized on thin-section computed tomography (81).
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Two spaces are said to be homeomor- Æ Æ Æ Æ Banisterine, Selegiline, and Parkinsons Disease 183 IGF-1 IGF-1 receptor Shc Crk PLC PI3 Kinase Ras p85 subunit p110 IRS-1 IP3 PKC Licened effects MAP Kinase Kinase p70p85 S6K MAP Kinase Ribosomal S6 Transcrip- tional changes Translational changes DNA synthesis Mitogenesis Antiapoptosis FIGURE 13.
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